Physics Links

http://www.livephysics.com/
A wealth of physics news, forums and teaching & learning tools.

http://phet.colorado.edu/
PhET: Free online science simulations.

http://www.quantum-physics.polytechnique.fr/
Quantum Physics Online.

http://www.compadre.org/
Resources for Physics and Astronomy Education.

Mathematica Links

http://www.wolfram.com/support/learn/
The Mathematica Learning Center.

http://www.wolframalpha.com/
Wolfram|Alpha: Computational Knowledge Engine.

Astronomy Links

http://hubblesite.org/
The official site for the Hubble Space Telescope.

http://www.zooniverse.org/home
Zooniverse is a great site containing an incredibly huge amount of information on the universe. There are several "Citizen Scientist" projects that anyone can get involved in such as helping astronomers classify galaxies, measure features of the Milky Way, or search for extra-solar planets. A great site for kids too!

Miscelaneous

http://plato.stanford.edu/
The Stanford Encyclopedia of Philosophy. Contains entries spanning far more that just philosophy.